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Radiation therapy and concurrent topotecan followed by maintenance triple anti-angiogenic therapy with thalidomide, etoposide, and celecoxib for pediatric diffuse intrinsic pontine glioma

The Pediatric Blood & Cancer journal has just released an interesting report about the use of a metronomic maintenance in children with pediatric diffuse intrinsic pontine gliomas (DIPGs). In the article entitled Radiation therapy and concurrent topotecan followed by maintenance triple anti-angiogenic therapy with thalidomide, etoposide, and celecoxib for pediatric diffuse intrinsic pontine glioma by Porkholm and al. the NOPHO group reports on 17% long term survivors (>24 months) and (…)

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