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Dose-Finding of Propranolol in combination with metronomic fixed oral cyclophosphamide based on Bivariate efficacy-tolerability outcome in patients with locally advanced or metastatic angiosarcoma : A collaborative and innovative phase I-II sequential trial

The Pr Sébastien Salas from the Adult Oncology Unit, CHU La Timone, AP-HM, Marseille, France has obtained funding for the PROPAN study (Dose-Finding of Propranolol in combination with metronomic fixed oral cyclophosphamide based on Bivariate efficacy-tolerability outcome in patients with locally advanced or metastatic angiosarcoma : A collaborative and innovative phase I-II sequential trial ).
Adrenergic processes stimulated by epinephrine and neorepinephrine drive the development of (…)

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