The Departments of Medical Oncology and Surgical Oncology of the Tata Memorial Hospital in Mumbai have just published in J Can Res Ther a study about the toxicity profile and efficacy of metronomic chemotherapy regimen (with twice daily celecoxib 200 mg and weekly methotrexate 15 mg/m2) for palliation in oral cavity cancers. Although not dealing with paediatric oncology this is a good exemple of what can metronomic chemotherapy can bring to patients in developing countries. Of note, Dr Banavali one of the authors of this article is also one of the Ambassador of MGHI