In this hypothesis paper the authors Jorge Eduardo Duque, Juliana Velez, Ismael Samudio and Enoch Lai from the Grupo de Terapia Celular y Molecular, Pontificia Universidad Javeriana, Bogotá DC, Colombia, the Centro Oncológico de Antioquia, Medellín, Colombia and the Shuang Ho Medical Hospital, Taipei Medical University, Taipei, Taiwan disucss the rationale to "reposition" metformine, an oral hypoglycemic agent as an anticancer agent and its combination with metronomic chemotherapy. The (...)