Dear Friends, your message is encouraging. In my humble opininio, however, I believe we need good in vivo studies in models other than micew and occasional rats Surely humanized mice are informative but they are not enough. I wonder if you know of any labs that are testing the effect of propranolol on canine breast tumors - ,benign and malignant; .Breast cancer in dogs sis said to be 30 x more frequent than in women. To end this message, I dont have access to the Xu article,could you spare a pdf for me? thanks for your attention and keep the good work! Michel Rabinovitch,M.D. (...)