The Pediatric Blood & Cancer journal has just released an interesting report about the use of a metronomic maintenance in children with pediatric diffuse intrinsic pontine gliomas (DIPGs). In the article entitled Radiation therapy and concurrent topotecan followed by maintenance triple anti-angiogenic therapy with thalidomide, etoposide, and celecoxib for pediatric diffuse intrinsic pontine glioma by Porkholm and al. the NOPHO group reports on 17% long term survivors (>24 months) (...)