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Metronomic delivery of cyclophosphamide is less detrimental to granulosa cell viability, ovarian function, and fertility than MTD

Dynes J, Osz K, Hooper A and Petrik J. from the Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada. have just published an article entitled Low Dose Metronomic Delivery of Cyclophosphamide is Less Detrimental to Granulosa Cell Viability and Ovarian Function Than Maximum Tolerated Dose Delivery in the Mouse in Biology of Reproduction. In this article they show using mice model that metronomic cyclophosphamide induces less (...)


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