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MGHI papers
Challenges and opportunities for cancer clinical trials in low- and middle-income countries
We are delighted and very proud regarding our latest piece that have been published in Nature Cancer entitled : Challenges and opportunities for cancer clinical trials in low- and middle-income countries This piece has been written by Bishal Gyawali from the Department of Oncology, Department of Public Health Sciences and Division of Cancer Care and[...]
‘Hard’ Drug Repurposing for Precision Oncology: the Missing Link?
As part of a "research topic" on drug repositioning and metronomic chemotherapy, opened for submission in Fontiers in Pharmacology, Pan Pantziarka, Gauthier Bouche and Nicolas André from the Anticancer Fund, Belgium , The George Pantziarka TP53 Trust, United Kingdom, the Department of Pediatric Hematology-Oncology, Assistance Publique Hôpitaux de[...]
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A mathematical model for the administration of temozolomide: comparative analysis of conventional and metronomic chemotherapy regimens.
Faivre C, Barbolosi D, Pasquier E, André N from INSERM UMR 911, Centre de Recherche en Oncologie Biologique et Oncopharmacologie and from the Metronomics Global Health Initiative have just published in Cancer Chemotherapy Pharmacology a new article entitled : A mathematical model for the administration of temozolomide: comparative analysis of[...]
Access to new drugs in paediatric oncology: can we learn from the ongoing ONC201 saga?
We are very proud to share our last piece published in the March issue of the Lancet Oncology The article entitled "Access to new drugs in paediatric oncology: can we learn from the ongoing ONC201 saga?" has been written by Nicolas André from the Department of Pediatric Oncology, La Timone University, Hospital of Marseille, APHM, Marseille 13005,[...]
Accidental Poisoning With 6-MP in a Sibling of Pediatric Patient Treated With Metronomic Maintenance Chemotherapy.
A recent article entitled "Accidental Poisoning With 6-MP in a Sibling of Pediatric Patient Treated With Maintenance Chemotherapy" has been published in the Journal of Pediatric Hematology and Oncology.
The article has been written by clinicians (Fernandez, Arnaud MD; Gervoise-Boyer, Marie J. MD; Chambost, Hervé MD, PhD; Coze, Carole MD, PhD; Andre,[...]
Beta-blockers disrupt mitochondrial bioenergetics & increase radiotherapy efficacy independently of BAR in medulloblastoma
We are very proud to share our latest publication entitled : Beta-blockers disrupt mitochondrial bioenergetics and increase radiotherapy efficacy independently of beta-adrenergic receptors in medulloblastoma from Maïlys Rossia, Julie Talbot, Patricia Pirisa, Marion LeGrand, Marie-Pierre Montero, Mélanie Matteudi, Emilie Agavnian-Couquiaud, Romain[...]
Can metronomic maintenance with weekly vinblastine prevent early relapse/progression after bevacizumab–irinotecan in children with low-grade glioma?
Marie Amélie Heng, Laetitia Padovani, Philippe Dory-Lautrec, Jean Claude Gentet, Arnaud Verschuur, Eddy Pasquier, Dominique Figarella-Branger, Didier Scavarda and Nicolas André from the Service d’hématologie et Oncologie Pédiatrique, AP-HM, the Metronomics Global Health Initiative, and the Aix-Marseille Université, INSERM, CRO2 UMR_S 911, Marseille[...]
Can Targeted Therapy be Successful without Metronomic Scheduling ?
Barton Kamen, Eddy Pasquier and Nicolas André have written for a special issue on target therapies for Currents Topics in Medicinal Chemistry a article entitled : Can Targeted Therapy be Successful without Metronomic Scheduling ? in which they discuss the importance of doses and schedule to increase specificity of anticancer treatments.
ABSTRACT[...]
Concentration- and schedule-dependent effects of chemotherapy on the angiogenic potential and drug sensitivity of vascular endothelial cells
Concentration- and schedule-dependent effects of chemotherapy on the angiogenic potential and drug sensitivity of vascular endothelial cells by Eddy Pasquier, Maria-Pia Tuset, Janine Street, Snega Sinnappan, Karen L. MacKenzie, Diane Braguer, Nicolas André, Maria Kavallaris from the Children’s Cancer Institute Australia for Medical Research, the[...]
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