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MGHI papers

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Maintenance chemotherapy in children with ALL exerts metronomic-like thrombospondin-1 associated anti-endothelial effect

Our lastest article entitled Maintenance chemotherapy in children with ALL exerts metronomic-like thrombospondin-1 associated anti-endothelial effect has just been published in Oncotarget.
This study has been performed the Service d’Hématologie et Oncologie Pédiatrique, Centre Hospitalo-Universitaire Timone Enfants and the Laboratoire d’Hématologie,[...]

Maintenance therapy for pediatric sarcoma: full throttle ahead?

We are delighted to announcve a new Metronomics Global Health Initiative publication !
Maintenance therapy for pediatric sarcoma: full throttle ahead? has been publisahed in Current opinion in Oncology as part of a sarcoma special issue. The piece has been written with Nadege Corradini from the HOPe-Pediatric Hematolgy and Oncology Institute, Leon[...]

METRO-PD1: Phase 1 study of nivolumab in combination with metronomic chemotherapy in children and adolescents with relapsing/refractory solid tumors

Our recent phase 1 trial exploring the combination of Nivolumab and metronomic chemotherapy entitled: METRO-PD1: Phase 1 study of nivolumab in combination with metronomic chemotherapy in children and adolescents with relapsing/refractory solid tumors has just been published in the European Journal of Cancer by Nicolas André, Marie Cécile Le Deley,[...]

Metronomic chemotherapy for children in low- and middle-income countries: survey of current practice and opinion of pediatric oncologists," has been accepted for publication in Journal of Global Oncology

We are please to announce taht our manuscript entitled : Metronomic chemotherapy for children in low- and middle-income countries: survey of current practice and opinion of pediatric oncologists by Revon-Rivière Gabriel, Banavali Shripad, Heississen Laila, Gomez Garcia Wendy, , Abdolkarimi Babak, Vaithilingum Manickavallie, Chi-Kong Li, Leung Ping[...]

Metronomic Chemotherapy in Pediatric Oncology: A Way Forward for Low-Income Countries?

This is an up to date review on metronomics for children living in Low Income Countries that has been posted on the Oncopedia website.You can find the pdf file bellow or you might log on the Oncopedia website where comments from oncologist will be added.

Metronomic Chemotherapy with the COMBAT Regimen in Advanced Pediatric Malignancies: A Multicenter Experience

The team of Pr J. Sterba from the department of Pediatric Oncology,School of Medicine, Brno, Czech Republic, has published the experience with the COMBAT metronomic regimen in 3 european institutions. The manuscript is accepted for publication in Oncology. The ful data will be presented during the 3rd Metronomic Meeting in Haifa. MGHI is associated[...]

Metronomic Chemotherapy: Direct Targeting of Cancer Cells after all?

Nicolas André, Kelvin Tsai, Manon Carré, Eddy Pasquier from the Service d’Hématologie et Oncologie Pédiatrique, Hôpital pour Enfants de La Timone, the Inserm CRO2 UMR_S 911, Aix-Marseille University, the CNRS, INSERM, Aix-Marseille University, Institut Paoli-Calmettes, CCRCM, Marseille, France and the Laboratories for Tumor Aggressiveness and Stemness;[...]

metronomic maintenance for locoregionally advanced nasopharyngeal carcinoma

We are very proud to shaer here a comment written by Robert Kerbel from the Department of Medical Biophysics, Biological Sciences Platform, Sunnybrook Research Institute, University of Toronto, Canada & Nicolas André from the Metronomics Global Health Initiative, Children Hospital of La Timone, AP-HM, Aix Marseille Université, Marseille, France taht[...]

Metronomic Maintenance Therapy for Rhabdomyosarcoma

Following the recent article in the Lancet Oncology from Bisogno et al. reporting a randomized trial in which addition of metronomic maintenance therapy (MMT) with vinorelbine plus cyclophosphamide for children with high-risk rhabdomyosarcoma resulted in a significant increase in overall and event-free survival; Nicolas ANDRE, Yuval SHAKED and[...]

Metronomic Maintenance With Weekly Vinblastine After Induction With Bevacizumab-Irinotecan in Children With Low-grade Glioma Prevents Early Relapse

An article entitled by Clémence Roux, Gabriel Revon-Riv, Laetitia Padovani from the children hospital of AP-HM and Nicolas André from AP-HM and MGHI entitled : Metronomic Maintenance With Weekly Vinblastine After Induction With Bevacizumab-Irinotecan in Children With Low-grade Glioma Prevents Early Relapse: has just been published in the Journal of[...]