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Metronomic in adult

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Metronomic chemotherapy : new rationale for new direction

Nat Rev Clin Oncol. 2010 Aug;7(8):455-65. Epub 2010 Jun 8. Metronomic chemotherapy: new rationale for new directions. Pasquier E, Kavallaris M, André N. Tumor angiogenesis is recognized as a major therapeutic target in the fight against cancer. The key involvement of angiogenesis in tumor growth and metastasis has started to redefine chemotherapy and (...)

Metronomic Chemotherapy : the book !

I t is our pleasure to announce the publication of the following book: Metronomic Chemotherapy : Pharmacology and Clinical Applications the editors are Guido Bocci and Giulio Francia With 19 chapters covering all fields of metronmic chemotherapy from the birth of the concept to updated clinical reviews. This book coversall aspects of metronomic (...)

Metronomic chemotherapy in advanced oral cancers

The Departments of Medical Oncology and Surgical Oncology of the Tata Memorial Hospital in Mumbai have just published in J Can Res Ther a study about the toxicity profile and efficacy of metronomic chemotherapy regimen (with twice daily celecoxib 200 mg and weekly methotrexate 15 mg/m2) for palliation in oral cavity cancers. Although not dealing with paediatric oncology this is a good exemple of what can metronomic chemotherapy can bring to patients in developing countries. Of note, Dr Banavali one of the authors of this article is also one of the Ambassador of MGHI

Metronomic cyclophosphamide & anti-tumor immunity: tumor model & drug schedule dependence of gene responses and their regulators.

In this recent preclinical work entitled Metronomic cyclophosphamide activation of anti-tumor immunity: tumor model, mouse host, and drug schedule dependence of gene responses and their upstream regulators published in BMC Cancer, the team from David Waxman, Division of Cell and Molecular Biology, Department of Biology and Bioinformatics Program, Boston (...)

Metronomic delivery of cyclophosphamide is less detrimental to granulosa cell viability, ovarian function, and fertility than MTD

Dynes J, Osz K, Hooper A and Petrik J. from the Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada. have just published an article entitled Low Dose Metronomic Delivery of Cyclophosphamide is Less Detrimental to Granulosa Cell Viability and Ovarian Function Than Maximum Tolerated Dose Delivery (...)

Metronomics@Mumbai2016 : special issue of the South Asian Journal of Cancer

A special issue of the Asian Journal of Cancer dedicated to the M@M2016 meeting has just been released. The full issue is in open access and can be found here Find bellow the editorial that introduce this special issue. More than thirty studies containing data on 1390 patients with various malignancies (544 with head neck cancer, 153 with ovarian (...)

Paediatric cancer in low-income and middle-income countries

in the Lancet Oncology, Ian Magrath, Eva Steliarova-Foucher, Sidnei Epelman, Raul C Ribeiro, Mhamed Harif, Chi-Kong Li, Rejin Kebudi, Scott D Macfarlane, Scott C Howard wrote a comprehensive review entitled : Paediatric cancer in low-income and middle-income countries in whihc they propose new strategy to figh cancer in MLIC. Acces to full text (...)

Response assessment in metronomic chemotherapy: RECIST or PERCIST?

In their recent publication in the Indian J Nucl Med, entitled Response assessment in metronomic chemotherapy: RECIST or PERCIST? Agrawal A, Purandare N, Shah S, Puranik A, Banavali S, Rangarajan from the Tata Memorial Hospital in Mumbay report that assessing metabolic respoense with PET-scan might be better the traditioanl CT evaluation. They (...)

Role of vascular normalization in benefit from metronomic chemotherapy.

FM Pekris, JW Baish , T. Stylianopoulos T, and RK Jain from the Cancer Biophysics Laboratory, Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia , Cyprus, the Department of Biomedical Engineering, Bucknell University, Lewisburg, the Cancer Biophysics Laboratory, Department of Mechanical and Manufacturing Engineering, (...)

Special section on Metronomic Chemotherapy in Cancer Letters

Special section on Metronomic Chemotherapy, Guest Edited by Ravi Kumar and A.K. Sood from the Department of Pharmaceutical Sciences, Texas A&M University, College Station, TX, USA and the Frank McGraw Memorial Chair in Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA has been published in Cancer Letters. This (...)