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Metronomic in children

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A case of relapsing spinal atypical AT/RT responding to metronomic vinorelbine-cyclophosphamid-celecoxib.

A recent case report entitled "A case of relapsing spinal atypical AT/RT responding to metronomic vinorelbine-cyclophosphamid-celecoxib" has just been published in Childs Nerv Sys by Gotti G, Biassoni V, Schiavello E, Spreafico F, Antonelli M, Calareso G, Pecori E, Gandola L, and Massimino M. from the Pediatric Unit of the Fondazione IRCCS Istituto (...)

A phase II trial of a multi-agent oral antiangiogenic (metronomic) regimen in children with recurrent or progressive cancer

Nathan J. Robison from Mark Kieran’s group in Boston just published a report of a phase II 5 drug regimen built upon the pioneer "4 drug regimen" published 8 years ago. The article is entitled "A phase II trial of a multi-agent oral anti-angiogenic (metronomic) regimen in children with recurrent or progressive cancer" was designed to evaluate the (...)

A pilot study of low-dose anti-angiogenic chemotherapy in combination with standard multiagent chemotherapy for patients with newly diagnosed metastatic ewing sarcoma family of tumors

In an article published very recently in Pediatric Blood and Cancer by the COG entitled : A pilot study of low-dose anti-angiogenic chemotherapy in combination with standard multiagent chemotherapy for patients with newly diagnosed metastatic ewing sarcoma family of tumors: A Children’s Oncology Group (COG) phase II study (NCT00061893) that aimed at (...)

Combination of metronomic cyclophosphamide and dietary intervention for neuroblastoma.

Morscher RJ, Aminzadeh-Gohari S Hauser-Kronberger C, Feichtinger RG, Sperl W, and Kofler B from the Laura Bassi Centre of Expertise-THERAPEP, Department of Pediatrics, Paracelsus Medical University, the Division of Medical Genetics, Medical University Innsbruck, the Department of Pathology, Paracelsus Medical University and the Department of (...)

Complete Remission and Long-term Survival in a Child With Relapsed Medulloblastoma With Extensive Osteosclerotic Bony Metastasis With a Novel Metronomic Chemobiological Approach.

The Tata Memorial Hospital in Mumbai has just published a interesting case report of a child with a relapsing medduloblastoma with extraneural metastasis who was successfully treated with a metronomic combination for 18 months.

Drug repurposing in pediatrics and pediatric hematology oncology.

In this review article to published online in Drug Discovery Today, J Blatt and SJ Corey from the University of North Carolina, USA explore the scope of drug repurposing in pediatric hematology oncology and highlight its potential. Drug repurposing in pediatrics and pediatric hematology oncology. lBatt J, Corey SJ. Drug Discov Today. 2012 Jul 23. (...)

Medication Errors on Oral Chemotherapy in Children With ALL in a Developing Country

Sapna Oberoi, Amita Trehan and Ram Kumar Marwaha from the Division of Haematology/Oncology in The Hospital for Sick Children,Toronto, Canadaa nd from the Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India have just published in Pediatric Blood and Cancer an article entitled Medication Errors on Oral (...)

Metronomic Chemotherapy and Palliative Radiotherapy as Salvage Treatment of Refractory or Relapsed Pediatric Solid Tumors

In a recent article published in Current Oncology entitled Metronomic Chemotherapy and Palliative Radiotherapy as Salvage Treatment of Refractory or Relapsed Pediatric Solid Tumors A.M. Ali and M.I. El-Sayed from the Department of Radiotherapy and Nuclear Medicine, South Egypt Cancer Institute, Assiut University, Al-methak Street, Assiut, Egypt (...)

Metronomic Chemotherapy as a New Strategy for End-stage Pediatric Oncology Patients in Iran

Mahdi Shahriari and Babak Abdolkarimi from the Pediatric Hematology-Oncology Division, and Department of Pediatrics of the Shiraz University of Medical Sciences in Iran have just published in the Middle East Journal of Cancer a letter entitled: Metronomic Chemotherapy as a New Strategy for End-stage Pediatric Oncology Patients in Iran. In this (...)

Metronomic Chemotherapy in Progressive Pediatric Malignancies: Old Drugs in New Package

A Bahl A and S Bakhshi from the Department of Medical Oncology, Institute Rotary Cancer Hospital, All India Institute of Medical Sciences in New Delhi have just published a reveiw about metronomic chemotherapy in the Indian Journal of Pediatrics you can acces the full text at the following adress : http://www.springerlink.com/content...