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Metronomic Chemotherapy for Burkitt Lymphoma in a Patient With HIV

Pankaj Dwivedi, Atul Kapse, Chaitali Bangurwar, Ankita Tamhane, Shripad Banavali from the Departments of Pediatric Oncology, Nuclear Medicine, Pathology, National Cancer Institute, Nagpur and Medical Oncology, Tata Memorial Centre, Mumbai, Maharashtra, India have published in the Journal of Pediatric Hematology Oncology a cas report entiteld : Metronomic Chemotherapy for Burkitt Lymphoma in a Patient With HIV

Burkitt lymphoma (BL) is an aggressive type of non-Hodgkin lymphoma (NHL). With high-dose combination chemotherapy, cure rates are excellent. Treatment for HIV-positive BL is similar to that for HIV-negative BL. Offering long-term intensive chemotherapy is difficult in resource-limited settings. Oral metronomic chemotherapy, though in vogue as a treatment modality, has limited evidence of its efficacy in HIV-positive BL. Here, we present the case of a child who was diagnosed with BL and HIV and administered metronomic chemotherapy, and also review the literature on the role of metronomic chemotherapy in non-Hodgkin lymphoma with and without HIV.

the case report is availabel here.