Metronomics Global Health Initiative

Nicolas André

Nicolas André auteur count 19 billets for Metronomics Global Health Initiative

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Michael RETSKY

Michael Retsky (Ph.D in physics from University of Chicago) made a career change from physics to cancer research. He is Editor-in-Chief of Journal of Bioavailability and Bioequivalence, on staff at Harvard School of Public Health, faculty at University College London, and Prof Adj at UANL, Monterrey, Mexico. He was on Judah Folkman’s staff at Harvard (...)

Metronomic Chemotherapy in Pediatric Oncology: A Way Forward for Low-Income Countries?

This is an up to date review on metronomics for children living in Low Income Countries that has been posted on the Oncopedia website.You can find the pdf file bellow or you might log on the Oncopedia website where comments from oncologist will be added.

Sourire A La Vie

En collaboration avec les médecins, l’association Sourire à la Vie propose aux enfants porteurs d’un cancer des activités physiques et artistiques adaptées à l’extérieur de l’hôpital. Sur le lieu du stage, les activités sont organisées sur mesure en fonction de la fragilité des enfants. L’équipe médicale valide la particpation et organise les soins nécessaires pour (...)


Dr. Kieran received his PhD from the University of Alberta and MD from the University of Calgary in Canada. He then completed a post-doctoral fellowship in molecular biology at the Pasteur Institute in Paris France followed by his residency in pediatrics at McGill University in Montreal, Canada. Dr Kieran then completed a fellowship in pediatric (...)

High-level Meeting on Non-communicable Diseases

High-level Meeting on Non-communicable Diseases Background The General Assembly in its resolution A/RES/65/238 decided that the high-level meeting of the General Assembly on the prevention and control of non-communicable diseases shall be held on 19 and 20 September 2011 in New York and that the high-level meeting shall address the prevention and (...)

Cancer joins AIDS, malaria as global health issue

Cancer joins AIDS, malaria as global health issue The fight against diseases like AIDS, malaria and tuberculosis has made Seattle a center for global health. Now, increasingly, the battle is including cancer — which might seem ridiculously impossible. Isn’t it hard enough to fight infectious diseases in poor countries? Can we afford to start talking (...)

Global move needed to battle cancer in poor countries

Global move needed to battle cancer in poor countries (AFP) – Jun 6, 2011 CHICAGO — A broad international effort is needed to halt the rapid spread of cancer in poor and middle-income countries, leaders from world cancer organizations said at a meeting in Chicago. The call for action came at the 47th annual conference of the American Society of Clinical (...)


After completing Metro-Mali 01 we aimed at developing a protocol that would be more efficient without increasing cost nor toxicity. We designed Metro-Mali 02 as a combination of metromomic chemotherapy and drug repositioning. Thus we added valproic acid as an HDAC inhibitor, an established new anticancer strategy. Valproic acid has already been (...)

Drug Repositioning

A model of sustainable drug development: recycling old drugs to turn them into long term anti-cancer targeted therapies Drug repositioning consists in using old drugs for new indications. The theoretical and pragmatic advantages to testing already established drugs for a potential effect on cancer cells are clear. The side-effects are known and have (...)

Metronomic Chemotherapy

Metronomic chemotherapy is based on the chronic administration of chemotherapeutic agents at relatively low, minimally toxic doses, and with no prolonged drug-free breaks ■ Metronomic chemotherapy was originally developed to overcome drug resistance by shifting therapeutic target from tumor cells to tumor vasculature ■ In the past decade, several pilot (...)