Nicolas André
Global move needed to battle cancer in poor countries
Global move needed to battle cancer in poor countries (AFP) – Jun 6, 2011 CHICAGO — A broad international effort is needed to halt the rapid spread of cancer in poor and middle-income countries, leaders from world cancer organizations said at a meeting in Chicago. The call for action came at the 47th annual conference of the American Society of Clinical (...)
Metro-Mali02
After completing Metro-Mali 01 we aimed at developing a protocol that would be more efficient without increasing cost nor toxicity. We designed Metro-Mali 02 as a combination of metromomic chemotherapy and drug repositioning. Thus we added valproic acid as an HDAC inhibitor, an established new anticancer strategy. Valproic acid has already been (...)
Drug Repositioning
A model of sustainable drug development: recycling old drugs to turn them into long term anti-cancer targeted therapies Drug repositioning consists in using old drugs for new indications. The theoretical and pragmatic advantages to testing already established drugs for a potential effect on cancer cells are clear. The side-effects are known and have (...)
Metronomic Chemotherapy
Metronomic chemotherapy is based on the chronic administration of chemotherapeutic agents at relatively low, minimally toxic doses, and with no prolonged drug-free breaks ■ Metronomic chemotherapy was originally developed to overcome drug resistance by shifting therapeutic target from tumor cells to tumor vasculature ■ In the past decade, several pilot (...)
Join in !
if you share our vision, if you think you can help us to make our dream come true, if you think we can help you with your own projects. do not hesitate. Contact us : Nicolas ANDRE Service d’Hématologie et Oncologie Pédiatrique Hôpital pour Enfants de La Timone AP-HM, Marseille France. mail : (...)
Metronomic preclinical models
Preclinical research is a crucial step toward the development of efficient anticancer treatments. The preclinical testing of metronomic treatments for children in developing countries is an important issue. These children often present with advanced metastatic disease that our model should reproduce. Children are also frequently suffering from (...)
A logo for the Metronomic Global Health Initiative
Here it is : The earth, the metronome, in our hands.... One planet, One People, One vision More with less for All ? We can do it Together ! With the participation of: Nicolas André
Venture philanthropy
Giving can make you feel good, giving can make you a better person: you are waiting for the right cause, we can give you the oppotunity be that beter person. If you believe in our action and want to be the one who made it happen by giving us the means to to put it into practice. You can help us by giving financial capital. Funding on a multi-year (...)
Change mentality : cancer is not a fatility in low income countries
In low income countries, for parents, for patients, cancer is a sentence. An anticipated long way to painful and distressing death, because treatment and care are lacking. Unless we take action now to make a difference, the existing health care infrastructure in low income countries will be overwhelmed by the predicted increase in cancer incidence. (...)
Building a metronomic website
We dream about a website that could explain our Metronomics Global Health Initiative, what it can bring to people suffering from cancer and connect people who share our vision....the birth of our project. With this website, we want to prove that we are a team of people who can develop innovative state-of-the-art projects promoting alternative global (...)
